Protein Interactions from the Molecular to the Domain Level

5 To my family and friends 6 7 List of Publications This thesis is based on the following papers, they will be referred to by their roman numerals in the text. and Hvidsten TR (2009) Using multi-data hidden Markov models trained on local neighborhoods of protein structure to predict residue residue contacts. (2012) Molecular recognition of a single sphingolipid species by a protein's transmembrane domain. Nature. 481 (7382): 525-529 iii. (2014) Identification of novel sphingolipid–binding motifs in mam-malian membrane proteins. Manuscript. iv. (2011) Systematic analysis of native membrane protein complexes in Escherichia coli. (2011) TIM23-mediated insertion of trans-membrane α-helices into the mitochondrial inner membrane The EMBO journal. 30 (6): 1003-1011 vii. Galian C, Björkholm P, Bulleid N, von Heijne G (2012) Efficient glycosylphosphatidylinositol (GPI) modification of membrane proteins requires a C-terminal anchoring signal of marginal hydropho-bicity. (2013) A short C-terminal tail prevents mis-targeting of hydrophobic mitochondrial membrane proteins to the ER.